Volume 2, Issue 2 (9-2022)                   Zoonosis 2022, 2(2): 1-12 | Back to browse issues page

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Alimolaei M, Asadabadi-safat A. The exploitation of zoonotic biological agents in bioterrorism: a potential threat. Zoonosis 2022; 2 (2) :1-12
URL: http://zoonosis.ir/article-1-43-en.html
Kerman branch, Razi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Kerman, Iran , m.alimolaei@rvsri.ac.ir
Abstract:   (29 Views)
The use of zoonotic biological agents in bioterrorism to cause injury or death is not a new concept. The term "bioterrorism", also known as biological attack, is the deliberate release of pathogenic microorganisms among human populations, livestock, and even food products, which leads to terror, and extensive economic damage by causing disease and death. The world has been involved in bioterrorism for hundreds of yearswhich dates back to the 14th century when corpses were thrown into enemy wells to poison drinking water. These agents include various bacteria, viruses, fungi, and toxins (with microbial, plant, or animal origin). More than 30 biological warfare agents have been identified and classified based on their characteristics and use, all of which are zoonotic except smallpox, cholera, and shigellosis. The Centers for Disease Control and Prevention (CDC) classifies biological agents into three groups; A, B, and C, and designates anthrax, botulism, plague, smallpox, tularemia, and viral hemorrhagic fevers as the group A agents, which pose the biggest risk for national security. Recently, the Covid-19 pandemic also raised many questions about the biological use of coronaviruses. This article investigates the relationship between biological agents of zoonosis that may be used in bioterrorism to prepare for the quick resolution of possible crises.
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Book Review: Review Article | Subject: Emerging and Re-Emerging
Received: 2022/07/28 | Accepted: 2022/09/21 | Published: 2022/11/23

1. Taylor LH, Latham SM, Woolhouse MEJ. Risk factors for human disease emergence. Philosophical Transactions of the Royal Society of London Series B: Biological Sciences. 2001;356(1411):983-9. [DOI:10.1098/rstb.2001.0888] [PMID] [PMCID]
2. Solodoukhina D. Food safety and bioterrorism from public health perspective. Advances in Food Protection: Springer; 2011. p. 17-25. [DOI:10.1007/978-94-007-1100-6_2] [PMCID]
3. Riedel S, editor Biological warfare and bioterrorism: a historical review2004 2004: Taylor & Francis.
4. Tumbarska AD. The non-lethal technologies against the terrorism. European Journal of Engineering and Technology Research. 2018;3(5):41-6. https://doi.org/10.24018/ejeng.2018.3.5.729 [DOI:10.24018/ejers.2018.3.5.729]
5. Pal M. Public health concern due to emerging and re-emerging zoonoses. International Journal of Livestock Research. 2013;3(1):56-62. [DOI:10.5455/ijlr.20130305071351]
6. Dudley JP, Woodford MH. Bioweapons, bioterrorism and biodiversity: potential impacts of biological weapons attacks on agricultural and biological diversity. Revue scientifique et technique-Office international des épizooties. 2002;21(1):125-38. [DOI:10.20506/rst.21.1.1328] [PMID]
7. Kortepeter M. Medical management of biological casualties handbook. 2001.
8. Bandyopahdyay L. Chemical And Biological Terrorism: The New Threat. Jadavpur Journal of International Relations. 2000;5(1):45-62. [DOI:10.1177/0973598400110005]
9. Office of technology assessment washington d. Proliferation of weapons of mass destruction: assessing the risks: DIANE Publishing; 1993.
10. Daszak P, Cunningham AA, Hyatt AD. Emerging infectious diseases of wildlife--threats to biodiversity and human health. science. 2000;287(5452):443-9. [DOI:10.1126/science.287.5452.443] [PMID]
11. Dobson A. The ecology and epidemiology of rinderpest virus in Serengeti and Ngorongoro Conservation Area. Serengeti II: Dynamics, management, and conservation of an ecosystem. 1995;2:485.
12. Chardonnet P, Kock R. African wildlife veterinary project: november 1998-june 2000. Final report. 2001.
13. Ryan CP. Zoonoses likely to be used in bioterrorism. Public health reports. 2008;123(3):276-81. [DOI:10.1177/003335490812300308] [PMID] [PMCID]
14. Mayor A, Fire G, Arrows P, Bombs S. Biological and chemical warfare in the ancient world. Overlook TP, New York. 2003:101-30.
15. Dembek ZF. Medical aspects of biological warfare: Textbooks of Military Medicine; 2008.
16. Sheolal R. Bioterrorism: A New Challenge for the Medical Discipline. Southern African Journal of Anaesthesia and Analgesia. 2003;9(1):48-52. [DOI:10.1080/22201173.2003.10872993]
17. Boserup A, Institute SIPR. The problem of chemical and biological warfare: a study of the historical, technical, military, legal and political aspects of CBW, and possible disarmament measures. 3. CBW and the law of war: Almquist & Wiksell; 1973.
18. Wheelis M. Biological warfare at the 1346 siege of Caffa. Emerging infectious diseases. 2002;8(9):971. [DOI:10.3201/eid0809.010536] [PMID] [PMCID]
19. Christopher LTCGW, Cieslak LTCTJ, Pavlin JA, Eitzen EM. Biological warfare: a historical perspective. Jama. 1997;278(5):412-7. [DOI:10.1001/jama.1997.03550050074036]
20. Bhalla DK, Warheit DB. Biological agents with potential for misuse: a historical perspective and defensive measures. Toxicology and applied pharmacology. 2004;199(1):71-84. [DOI:10.1016/j.taap.2004.03.009] [PMID]
21. Jansen H-J, Breeveld FJ, Stijnis C, Grobusch MP. Biological warfare, bioterrorism, and biocrime. Clinical Microbiology and Infection. 2014;20(6):488-96. [DOI:10.1111/1469-0691.12699] [PMID] [PMCID]
22. Carus WS. Bioterrorism and biocrimes: the illicit use of biological agents since 1900. National Defense University Washington DC; 2001. [DOI:10.21236/ADA402108]
23. Hugh-Jones M. Global trends in the incidence of anthrax in livestock. Salisbury med Bull. 1990;68:2-4.
24. Pugh AO, Davies JCA. Human anthrax in Zimbabwe. Salisbury Medical Bulletin. 1990;68(special supplement):32-3.
25. Kobuch WE, Davis J, Fleischer K, Isaacson M, Turnbull PCB. A clinical and epidemiological study of 621 patients with anthrax in western Zimbabwe. Salisbury Medical Bulletin. 1990;68:34-8.
26. Lawrence JA, Foggin CM, Norval RA. The effects of war on the control of diseases of livestock in Rhodesia (Zimbabwe). The Veterinary Record. 1980;107(4):82-5. [DOI:10.1136/vr.107.4.82] [PMID]
27. Kaufmann AF, Meltzer MI, Schmid GP. The economic impact of a bioterrorist attack: are prevention and postattack intervention programs justifiable? Emerging infectious diseases. 1997;3(2):83. [DOI:10.3201/eid0302.970201] [PMID] [PMCID]
28. Chomel BB, Sun B. Bioterrorism and invasive species. Revue scientifique et technique. 2010;29(2):193. [DOI:10.20506/rst.29.2.1977]
29. Agarwal R, Shukla SK, Dharmani S, Gandhi A. Biological warfare-an emerging threat. JAPI. 2004;52(9):733-8.
30. Ban J. Agricultural biological warfare: An overview: Chemical and Biological Arms Control Institute The Arena, Washington; 2000.
31. Ligon BL, editor Plague: a review of its history and potential as a biological weapon2006: Elsevier. [DOI:10.1053/j.spid.2006.07.002] [PMID]
32. eselson M, Guillemin J, Hugh-Jones M, Langmuir A, Popova I, Shelokov A, et al. The Sverdlovsk anthrax outbreak of 1979. Science. 1994;266(5188):1202-8. [DOI:10.1126/science.7973702] [PMID]
33. Franz DR. Preparedness for an anthrax attack. Molecular aspects of medicine. 2009;30(6):503-10. [DOI:10.1016/j.mam.2009.07.002] [PMID]
34. Perkins SD, Smither SJ, Atkins HS. Towards a Brucella vaccine for humans. FEMS microbiology reviews. 2010;34(3):379-94. [DOI:10.1111/j.1574-6976.2010.00211.x] [PMID]
35. Pallipparambil GR. The Surat plague and its aftermath. Unpublished essay Available at: http. 2014.
36. Sidwell RW, Smee DF. Viruses of the Bunya-and Togaviridae families: potential as bioterrorism agents and means of control. Antiviral research. 2003;57(1-2):101-11. [DOI:10.1016/S0166-3542(02)00203-6]
37. Bossi P, Tegnell A, Baka A, Van Loock F, Hendriks J, Werner A, et al. Taskforce on Bioterrorism (BICHAT). Public Health Directorate, European Commission, Luxembourg BICHAT guidelines for the clinical management of tularemia and bioterrorism-related tularemia Euro Surveill. 2004;9(12):E9-E10. [DOI:10.2807/esm.09.12.00508-en] [PMID]
38. Chipman R, Slate D, Rupprecht C, Mendoza M. Downside risk of wildlife translocation. 2008.
39. Singer A, Kauhala K, Holmala K, Smith GC. Rabies in northeastern Europe-the threat from invasive raccoon dogs. Journal of Wildlife Diseases. 2009;45(4):1121-37. [DOI:10.7589/0090-3558-45.4.1121] [PMID]
40. Ksiazek TG, Erdman D, Goldsmith CS, Zaki SR, Peret T, Emery S, et al. A novel coronavirus associated with severe acute respiratory syndrome. New England journal of medicine. 2003;348(20):1953-66. [DOI:10.1056/NEJMoa030781] [PMID]
41. Li Q, Guan X, Wu P, Wang X, Zhou L, Tong Y, et al. Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. New England journal of medicine. 2020.
42. Zheng M, Gao Y, Wang G, Song G, Liu S, Sun D, et al. Functional exhaustion of antiviral lymphocytes in COVID-19 patients. Cellular & molecular immunology. 2020;17(5):533-5. [DOI:10.1038/s41423-020-0402-2] [PMID] [PMCID]
43. Zhang J, Litvinova M, Wang W, Wang Y, Deng X, Chen X, et al. Evolving epidemiology and transmission dynamics of coronavirus disease 2019 outside Hubei province, China: a descriptive and modelling study. The Lancet Infectious Diseases. 2020;20(7):793-802. [DOI:10.1016/S1473-3099(20)30230-9]
44. Dehghani A, Masoumi G. Could SARS-CoV-2 or COVID-19 be a biological weapon? Iranian journal of public health. 2020;49(Suppl 1):143. [DOI:10.18502/ijph.v49iS1.3691]
45. Wagar EA, Mitchell MJ, Carroll KC, Beavis KG, Petti CA, Schlaberg R, et al. A review of sentinel laboratory performance: identification and notification of bioterrorism agents. Archives of pathology & laboratory medicine. 2010;134(10):1490-503. [DOI:10.5858/2010-0098-CP.1] [PMID]
46. Li F, Du L. MERS coronavirus: an emerging zoonotic virus. MDPI; 2019. p. 663. [DOI:10.3390/v11070663] [PMID] [PMCID]
47. Nathan W, Claire P-D, Jared D. Origins of major infectious diseases. Nature. 2007;447(17):279-83. [DOI:10.1038/nature05775] [PMID] [PMCID]
48. Ginsberg JR, Mace GM, Albon S. Local extinction in a small and declining population: wild dogs in the Serengeti. Proceedings of the Royal Society of London Series B: Biological Sciences. 1995;262(1364):221-8. [DOI:10.1098/rspb.1995.0199] [PMID]
49. Kelly MJ. Lineage loss in Serengeti cheetahs: consequences of high reproductive variance and heritability of fitness on effective population size. Conservation Biology. 2001;15(1):137-47. [DOI:10.1111/j.1523-1739.2001.99033.x]
50. Simpson E. The poor man's nuclear bomb. 2014.

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